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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1E
All Species:
17.27
Human Site:
T203
Identified Species:
38
UniProt:
P10412
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10412
NP_005312.1
219
21865
T203
P
K
A
A
K
P
K
T
A
K
P
K
A
A
K
Chimpanzee
Pan troglodytes
XP_001172808
221
22291
S205
P
K
A
A
K
P
K
S
G
K
P
K
V
T
K
Rhesus Macaque
Macaca mulatta
P40286
208
22075
K198
P
K
L
T
Q
H
H
K
A
N
I
R
K
A
T
Dog
Lupus familis
XP_853847
290
29282
T270
C
G
S
A
A
P
W
T
S
G
S
A
G
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
T203
P
K
A
A
K
P
K
T
S
K
P
K
A
A
K
Rat
Rattus norvegicus
P15865
219
21969
T203
P
K
A
A
K
P
K
T
S
K
P
K
A
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
A206
P
K
A
A
K
P
K
A
A
K
P
K
S
A
K
Chicken
Gallus gallus
P08284
219
22026
A203
P
K
A
A
K
P
K
A
T
K
P
K
A
A
K
Frog
Xenopus laevis
P06893
220
22422
V205
K
S
P
A
K
A
K
V
A
K
P
K
A
A
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
T243
K
K
A
S
V
S
A
T
A
K
K
P
K
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
K195
P
K
T
A
K
P
K
K
P
A
X
K
K
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
55.7
57.2
N.A.
94
95.4
N.A.
79.8
73.9
58.6
N.A.
N.A.
43.3
N.A.
N.A.
41.1
Protein Similarity:
100
87.3
68
62
N.A.
95.4
97.2
N.A.
87
79.4
66.3
N.A.
N.A.
52.3
N.A.
N.A.
50.6
P-Site Identity:
100
73.3
26.6
20
N.A.
93.3
93.3
N.A.
86.6
86.6
66.6
N.A.
N.A.
46.6
N.A.
N.A.
53.3
P-Site Similarity:
100
80
40
46.6
N.A.
100
100
N.A.
93.3
86.6
66.6
N.A.
N.A.
53.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
64
82
10
10
10
19
46
10
0
10
46
82
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
10
10
0
0
10
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
19
82
0
0
73
0
73
19
0
73
10
73
28
0
73
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
73
0
10
0
0
73
0
0
10
0
64
10
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% R
% Ser:
0
10
10
10
0
10
0
10
28
0
10
0
10
10
0
% S
% Thr:
0
0
10
10
0
0
0
46
10
0
0
0
0
10
10
% T
% Val:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _